[28P02-200S] Preparation and evaluation of a chromosome-integrated luciferase reporter yeast and double-gene disruptants for sensitive detections of DNA damage

○Kosuke Yamamoto¹, Shintaro Tochikawa¹, Yuu Hirose¹, Toshihiko Eki¹ (1. Dept. Appl. Chem. Life Sci., Toyohashi Univ. Tech.)

[28P02-201S] Construction and characterization of the yeast-mediated reporter assay using the improved luciferase yNanoluc

○Minami Shichinohe¹, Shintarou Tochikawa¹, Hirose Yu¹, Eki Toshihiko¹ (1. Toyohashi Tech)

[28P02-202] Occurrences of organotin compounds in various textile products marketed in Nagoya in recent years

○Tetsuo Hamasaki¹ (1. Department of Environmental Hygiene, Nagoya City Public Health Research Institute)

[28P02-203] Development of a screening method for therapeutic agents for erectile dysfunction and their analogues by supercritical fluid chromatography coupled with quadrupole time-of-flight mass spectrometry (SFC-QTOF-MS)

○Maiko Kawamura¹, Shiho Sakaida¹, Saisho Kazuhiro¹, Takashi Hakamatsuka¹, Ruri Kikura-Hanajiri¹ (1. National Institute of Health Sciences)

[28P02-204] Assessment of leaf-to-smoke migration of tobacco-specific nitrosamines in combustible cigarettes and heat-not-burn tobacco

○Atsushi Ishizaki¹, Hiroyuki Kataoka¹ (1. School of Pharmacy Shujitsu University)

[28P02-205] Determination of Nicotine eluted from heat-not-burn tobacco cartridges and its application in the medical education program

○Kimiko Hirata¹, Masao Katsumata¹, Maiko Sato¹, Yukiyo Hirata¹, Hirofumi Inagaki¹, Tomoyuki Kawada¹ (1. Nippon Medical School )

[28P02-206] Study of thermal degradation products derived from tryptamin derivatives using GC/MS and GC/QTOFMS

○Sakumi Mizutani¹, Maiko Kawamura¹, Takashi Hakamatsuka¹, Ruri Kikura-Hanajiri¹ (1. National Institute of Health Sciences)

[28P02-207] Sensitive analysis of advanced glycation end products AGEs in foods by LC-MS/MS

Nanba Takuya¹, Tanino Yuichi¹, ○Hiroyuki Kataoka¹ (1. School of Pharmacy, Shujitsu University)

[28P02-208S] Construction of a glycation model system and analysis of the inhibitory effects of food components on AGEs formation

○Yasuyuki Kono¹, Junpei Tada¹, Hiroyuki Kataoka¹ (1. School of Pharmacy, Shujitsu University)

[28P02-209] Application of the quantitative ¹H-NMR method for the determination of LSD derivatives in illegal products

○Rie Tanaka¹, Kawamura Maiko¹, Takashi Hakamatsuka¹, Ruri Kikura-Hanajiri¹ (1. National Institute of Health Sciences)

[28P02-210] Development of Cannabinoid analysis with QuEChERS in Cannabis-infused foods of seized samples.

○DAISUKE KURAKAMI¹ (1. NCD, Touhoku Regional, MHLW)

[28P02-211] Phylogenetic analysis of Cannabis sativa L. by MIG-seq

○Tadashi Yamamuro¹, Yuko T Iwata¹, Yuki Okada¹, Hiroki Segawa¹, Kenji Kuwayama¹, Kenji Tsujikawa¹, Tatsuyuki Kanamori¹ (1. National Research Inst. of Police Sci.)

[28P02-212] Estimation of the period of continuous ingestion of drugs based on micro-segmental hair analysis

○Kenji Kuwayama¹, Hajime Miyaguchi¹, Tatsuyuki Kanamori¹, Kenji Tsujikawa¹, Tadashi Yamamuro¹, Hiroki Segawa¹, Yuki Okada¹, Yuko Iwata¹ (1. NRIPS)

[28P02-213] Reduction of Flunitrazepam by saliva

○Tomoya Takeda¹ (1. Forensic Sci. Lab., Fukushima Pref. Police H.Q.)

[28P02-214] Development of GC-FID method with QuEChERS for quantification of Δ9-THC in Cannabis-infused foods

○Tachi Katsumi¹, Daisuke Kurakami², Kei Ieuji³, Yukari Tsumura¹ (1. Narcotics Control Department, Kanto-shi'netu Regional Bureau of Health and Welfare(Kanto NCD),Ministry of Health,Labour and Welfare(MHLW), 2. Tohoku NCD,MHLW, 3. Kyushu NCD,MHLW)

[28P02-215] Revision of the pyridine-pyrazolone method for cyanide analysis

○Yuki Okada¹, Hajime Miyaguchi¹ (1. National Research Institute of Police Science)

[28P02-216] Analysis of beta blockers and their metabolites using LC-MS/MS

○Keiko Tonooka-Kubota¹, Masaru Terada¹, Atsuna Kashihara¹, Tatsuo Shinozuka¹ (1. Yokohama Univ. Pharm.)

[28P02-217] Urinary excretion profiles of etizolam and its main metabolites after a single oral dose

○Misato Wada¹, Noriaki Shima¹, Shuntaro Matsuta¹, Keiko Sasaki¹, Tooru Kamata¹, Munehiro Katagi¹ (1. Forensic Sci. Lab. Osaka Pref. Police)

[28P02-218] Development of a Simultaneous Analytical Method For Glufosinate, Glyphosate, and AMPA in Drinking Water Using HPLC-FL

○Yasuko Hattori¹, Tomomi Harada¹, Minae Watanabe¹, Takashi Tanahashi¹ (1. Aichi Prefectural Institute of Public Health)

[28P02-219] Standard test method for air: Sampling and analysis of volatile organic compounds by solvent extraction/gas chromatography-mass spectrometry - pumped sampling

○Maiko Tahara¹, Shinobu Sakai¹, Aya Onuki², Ikue Saito², Masahiro Chiba³, Shiori Oizumi³, Reiko Tanaka⁴, Takashi Yamanouchi⁴, Hiroyuki Ohno⁵, Takanari Wakayama⁵, Yuko Yokoyama⁶, Osamu Endo⁷, Akira Toriba⁸, Daisuke Nakajima⁹, Eiji Fujimori¹⁰, Hideto Jinno¹¹, Toshiko Tanaka-Kagawa¹² (1. NIHS, 2. Tokyo Metropolitan Inst. Public Health, 3. Hokkaido Inst. Public Health, 4. Yokohama City Inst. Health, 5. Nagoya City Public Health Res. Inst., 6. Chiba Pref. Inst. Public Health, 7. Azabu Univ., 8. Grad. Sch. Biomed. Sci., Nagasaki Univ., 9. NIES, 10. Natl. Environ. Res. Training Inst., 11. Facul. Pharm. Meijo Univ., 12. Yokohama Univ. Pharm.)

[28P02-220] Methods of Analysis in Health Science : Qualitative and Quantitative Method for Trichothecene Mycotoxins and Zearalenone by LC/MS/MS or Histamine Measurement using the Enzymatic Method

○Toshihiro Nagayama¹, Naoki Mochizuki², Shiro Miyake³, Hiroyuki Nakagawa⁴, Kazuhiko Shimoji⁵, Takashi Kojima⁶, Satoshi Takatori⁷, Ichiro Takano¹, Satoru Nemoto⁸, Kazushi Mizukoshi⁹, Takashi Miyashita¹⁰ (1. Meiji Pharmaceutical University, 2. Yokohama University of Pharmacy, 3. Azabu University, 4. National Agriculture and Food Research Organization, 5. Kikkoman Biochemifa Co., 6. Teikyo University of Science, 7. Osaka Institute of Public Health, 8. National Institute of Health Sciences, 9. Japan Food Research Laboratories, 10. Kewpie Corporation)

[28P02-221] Analytical method of mercury in cosmetic products

○Yoshiaki Ikarashi¹, Tomoko Obama¹, Mitsuya Yoshida², Junko Yasuda³, Tetsuya Kuze⁴, Junko Nomura⁵, Shigeki Mori⁶, Katsuhiro Takano⁷, Takashi Kojima⁸, Makiko Fujii⁹ (1. NIHS, 2. Japan Food Res. Lab., 3. KOSE, 4. Kanebo Cosmetics, 5. Shiseido, 6. POLA Chemical, 7. JCIA, 8. Teikyo Univ. Sci., 9. Nihon Univ.)

[28P02-222] Investigation of microwave acid digestion conditions for the determination of antimony in cosmetic products

○Reiji Kubota¹, Takumi Akiyama¹, Yoshiaki Ikarashi¹ (1. National Institute of Health sciences)

[28P02-223] Quantitative test method for nitrite using the diazotization

○Kyoko Sato¹, Takahiro Sasaki², Hikaru Sakurai³, Akira Shimoyama⁴, Haruko Sekido⁵, Atsuko Tada¹, Shoko Terami¹, Shoichi Tahara², Takahiko Hara⁶, Takudo Ito⁶, Shinji Yamamoto⁷, Mika Yoshida⁸ (1. NIHS, 2. Tokyo Metr. Inst. Pub. Health., 3. Yokohama City. Inst. Pub. Health., 4. JFIC, 5. Kanagawa Pref. Inst. Pub. Health., 6. JIAFE, 7. Incorporated Foundation Tokyo Kenbikyo-in, 8. JFRL)

[28P02-224S] Functional analysis of Kaposi's Sarcoma associated Herpes Virus(KSHV) ORF21

○Tatsuo YAMAGUCHI¹, Tadashi WATANABE¹, Yuichi SEKINE¹, Masahiro FUJIMURO¹ (1. Department of Cell Biology, Kyoto Pharmaceutical University)

[28P02-225] Antimicrobial activities of D-peptide with an added N- or C-terminal cysteine

○Maki Kamiya Ohno¹, Teruo Kirikae², Eisaku Yoshihara³, Fumiko Kirikae², Atsushi Ohnishi¹, Isao Ishida¹ (1. Fac. Pharm. Sci., Teikyo Heisei Univ., 2. Juntendo Univ. Sch. of Med., 3. Tokai Univ. Sch. of Med.)

[28P02-226S] L-glutamine regulates PPARγ in adipocytes.

○Yuya Yamaji¹, Mayu Hashimoto¹, Kentarou Ishii¹, Katsuhiko Takahashi¹, Nobuaki Higashi¹ (1. Biochem., Hoshi Univ.)

[28P02-227] Metallothionein is important for improving lifestyle-related diseases by zinc supplementation

○Maki Fujino¹, Takashige Kawakami¹, Yoshito Kadota¹, Masahisa Inoue¹, Hitomi Fujishiro¹, Daigo Sumi¹, Shinya Suzuki¹ (1. Fac. Pharm. Sci., Tokushima Bunri Univ.)

[28P02-228S] Promoting mechanism of metallothionein gene knockout on lipid accumulation in AML12 murine hepatic cell line.

○Kanako Ikeda¹, Yoshito Kadota¹, Takashige Kawakami¹, Shinya Suzuki¹ (1. Fac. Pharmaceut. Sci., Tokushima Bunri Univ.)

[28P02-229] Metabolomics for mouse model of pregnant fatty liver

○Takashige Kawakami¹, Yoshito Kadota¹, Tomomi Abe¹, Masahisa Inoue¹, Shinya Suzuki¹ (1. Fac. Pharm. Sci., Tokushima Bunri Univ.)

[28P02-230] Abnormal circadian rhythm in corticosterone-treated mice before the onset of diabetes

○Reiko Iwadate¹, Hiroshi Kawai¹ (1. Facul. Pharm., Josai Univ.)

[28P02-231] Improvement of renal tubular epithelial cell injury by fatty acid uptake by suppression of CD36 expression

○Yasushi Kawasaki¹, Mei Kaneko¹, Miho Karimazawa¹, Yuki Katsumata¹, Akinori Sugiyama¹ (1. Dept. Health Chem., Sch. Pharm., Iwate. Med. Univ.)

[28P02-232] The Association between changes in DNA methyltransferase expression and cytotoxicity by inflammatory responses in renal tubular epithelial cells

○Takehiro Hasuda¹, Yasushi Kawasaki¹, Toshikazu Watanabe¹, Mei Kaneko¹, Mana Tateoka¹, Rika Asao¹, Akinori Sugiyama¹ (1. Dept. Health Chem., Sch. Pharm.,Iwate. Med. Univ)

[28P02-233S] Anti-inflammatory effects of SGLT2 inhibitors on vascular endothelial cells

○Rika Asao¹, mana tateoka¹, takehiro hasuda¹, yasushi kawasaki¹, toshikazu watanabe¹, mei kaneko¹, akinori sugiyama¹ (1. Dept. Health Chem., Sch. Pharm., Iwate. Med. Univ)

[28P02-234] The anti-inflammatory effect of glycation products dihydropyrazines

○Madoka Esaki¹, Takumi Ishida², Yuu Miyauchi¹, Shinji Takechi¹ (1. Fac. Pharmaceut. Sci., Sojo Univ, 2. Sch. Pharm. at Fukuoka, Int. Univ. Health & Welfare)

[28P02-235] The generation/accumulation of intracellular toxic AGEs (TAGE) triggers numerous types of cell damage

○Masayoshi Takeuchi¹, Akiko Sakasai-Sakai¹, Takanobu Takata¹, Jun-ichi Takino², Yoshiki Koriyama³, Chigusa Kikuchi⁴, Ayako Furukawa³, Kentaro Nagamine⁵, Takamitsu Hori², Tamihide Matsunaga⁴ (1. Med. Res. Inst., Kanazawa Med. Univ., 2. Facul. Pharmaceut. Sci., Hiroshima Int. Univ., 3. Grad. Sch. Facul. Pharmaceut. Sci., Suzuka Univ. Med. Sci., 4. Grad. Sch. Pharmaceut. Sci., Nagoya City Univ., 5. Facul. Health Sci., Hiroshima Int. Univ.)

[28P02-236] Toxic advanced glycation end products (TAGE) is involved in the development of diabetes-derived Alzheimer's disease.

○Ryuto Nasu¹, Ayako Furukawa², Masayoshi Takeuchi³, Yoshiki Koriyama ¹ (1. Grad. Sch. of Pharm. Sci., Suzuka Univ. of Med. Sci., 2. Fac. of Pharm. Sci., Suzuka Univ. of Med. Sci., 3. Dept. of Adv. Med., Med. Kanazawa Med. Univ.)

[28P02-237] Suppression of RasGRP2 on enhanced vascular permeability by advanced glycation end products

○Takamitsu Hori¹, Takuma Sato¹, Kentaro Nagamine², Masayoshi Takeuchi³, Junichi Takino¹ (1. Fac. of Pharm. Sci., Hiroshima International Univ., 2. Fac. of Health. Sci., Hiroshima International Univ., 3. Dept. of Advanced Med., Med. Res. Inst., Kanazawa Med. Univ.)

[28P02-238] Suppression of autophagy by RASGRP2 in vascular endothelial cells

○Takuma Sato¹, Junichi Takino¹, Kentaro Nagamine², Takamitsu Hori¹ (1. Fac. of Pharm. Sci., Hiroshima International Univ., 2. Fac. of Health Sci., Hiroshima International Univ.)

[28P02-239] Estrogen sulfotransferase, SULT1E1, highly expresses in the endothelial cells overlying atherosclerotic plaques

○Akira Sato^1,2, Hinako Watanabe¹, Miyuki Yamazaki¹, Eiko Sakurai¹, Keiichi Ebina^1,2 (1. Dept. Pharm. Health Sci., Fac. Pharm., Iryo Sosei Univ., 2. Grad. Sch. Life Sci. Technol., Iryo Sosei Univ.)

[28P02-240] Effect of high fat diet on the expression of adhesion molecules in vascular endothelial cells under the cancer metastasis of mice

○Sayuri Hiraishi¹, Yasuo Kagawa¹, Shuichi Horie¹ (1. Kagawa Nutrition University)

[28P02-241] Analysis of chemical compounds generated from Japanese little cigar brands

○Yohei Inaba¹, Shigehisa Uchiyama¹, Kanae Bekki¹, Akira Ushiyama¹ (1. National Institute of Public Health)

[28P02-242S] Determination of Aromatic Amines in Mainstream Smoke Using LC/MS/MS

○Natsumi Gunji¹, Yohei Inaba², Shigehisa Uchiyama^2,3, Hiroko Tobari¹, Yusuke Hori¹, Akira Ushiyama² (1. Dept. Pharm., Tokyo Univ Pharm & Life Sci., 2. Natl Inst Public Health., 3. Grad. Sch. Tech., Chiba Univ.)

[28P02-243S] Analysis of metals contained in tobacco leaves and mainstream tobacco smoke

○Ryusei Setoguchi¹, Youhei Inaba², Shigehisa Uchiyama^2,3, Hiroko Tobari¹, Yusuke Hori¹, Akira Usiyama² (1. Dept. Pharm., Tokyo Univ Pharm & Life Sci, 2. Natl Inst Public Health, 3. Grad. Sch. Tech., Chiba Univ)

[28P02-244] The association of health examination results and health habit improvement with population health: The analysis of National Database Open Data

○Yasuhiro Jinno¹, Hideaki kato², Satoshi Asano², Shigeharu Tanei³, Yukinori Nagakura¹ (1. School of Pharmacy at Fukuoka, International University of Health and Welfare, 2. School of Pharmacy, International University of Health and Welfare, 3. Faculty of Pharmaceutical Sciences, Nihon Pharmaceutical University)

[28P02-245] Effects of sulforaphane and allyl isothiocyanate on the differentiation of 3T3-L1 preadipocytes into mature adipocytes

○Satoru Sakuma¹, Keiichiro Okuhira¹ (1. Osaka Univ. Pharmaceut. Sci.)

[28P02-246S] Pulmonary effect of exposure to Fe3O4-PEG-PLGA nanoparticles in wild type and Nrf2 knockout mice

○Harue Sato¹, Cai Zong¹, Sahoko Ichihara², Ken Itoh³, Masayuki Yamamoto⁴, Sonja Boland⁵, Armelle Baeza-Squiban⁵, Gaku Ichihara¹ (1. Fac. Pharm. Sci., Tokyo Univ. of Sci., 2. Sch. Med., Jichi Med. Univ., 3. Grad. Sch. Med., Hirosaki Univ., 4. Grad. Sch. Med., Tohoku Univ., 5. Univ. of Paris)

[28P02-247] Measurement of Stereoisomer of Tadalafil and Tadalafil analogues found in dietary supplements

○Tomohide Fukiwake¹, Midori Yamazaki¹, Kazunaga Takahashi¹, Takahiro Doi², Masami Kawaguchi², Keigo Enomoto¹, Hiroki Yoshino¹, Katuya Uchimoto¹, Maki Nishimura¹ (1. Chiba Prefectural Institite of Public Health, 2. Osaka Institute of Public Health)

[28P02-248] Characteristics and elution behavior of ion-exchange polymer solid-phase extraction columns used for food analysis pretreatment

○Manabu Takayanagi¹, Takumi Kunieda¹, Masato Ono¹, Yuuko Yui¹, Shigenori Oota¹ (1. GL Sciences Inc.)

[28P02-249] A Study on Evaluation Method of Food for Dysphagic Patients

○Mika Shirao¹, Mayumi Ikegami² (1. Jissen Women's Univ., 2. Hosh Univ.)

[28P02-250] Airborne trichomes in Sapporo for nine years since 2012

○Shinji Takeuchi¹, Hirashima Koki¹ (1. Hokkaido Inst. Public Health)

[28P02-251] Study of pollen concentration collected with Burkard sampler in Sapporo, 2020

○Koki Hirashima¹, Satoshi Kobayashi¹, Shinji Takeuchi¹ (1. Hokkaido Inst. Public Health)

[28P02-252S] Construction of anemia-induced discrimination model based on structural characteristics of chemical substances

○Takaho Asai¹, Yuki Shimizu¹, Takamitsu Sasaki¹, Takuomi Hosaka¹, Shizu Ryota¹, Kouichi Yoshinari¹ (1. Sch. of Pharm. Sci., Univ. of Shizuoka)

[28P02-253S] Analysis of the relationship between enzyme induction using thyroid hypertrophy as a marker and lobular central hepatocyte hypertrophy: An attempt using pesticide toxicity test data

○Naoki Shibata¹, Ryota Shizu¹, Takuomi Hosaka¹, Yuichiro Kanno¹, Kouichi YoshYoshinari¹ (1. Sch. Pharm. of Sci., Univ. of Shizuoka)

[28P02-254S] The reason why Okinawa is no longer the longest-lived prefecture in Japan and what to do to resolve the current situation

○Masafumi Shiokawa¹, Masaki Takaishi¹, Satoshi Asano¹ (1. Pharm. Sci., IUHW.)

[28P02-255S] The effect of subjective well-being on illness and the effect of lifestyle on subjective well-being

○Erika Kikuchi¹, Masaki Takaishi¹, Satoshi Asano¹ (1. Pharm. Sci., IUHW.)

[28P02-256] Survey on the status of pharmacies' response to patients during an outbreak of a new coronavirus

○Kayoko Ozeki¹ (1. Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine)

[28P02-257] Activity report and vision as school pharmacist - About area contribution and a problem.

○Michiko Goroumaru-Shinkai¹, Jun Kuroda¹, Satoshi Muto², Maki Shimizu¹, Hideaki Ichiba¹, Kenji Narusuye¹, Katsue Nakazawa¹, Sumiko Iwasa², Chikako Ishikawa², Masako Kinoshita¹ (1. Phar.Sci., Toho-Univ., 2. Former Phar.Sci., Toho-Univ.)

[28P02-L010] Speciation analysis of arsenic compounds in blood samples by liquid chromatography–inductively coupled plasma–tandem mass spectrometry

○Yuko Kazui¹, Hajime Miyaguchi¹ (1. National Research Institute of Police Science)

Session information

[28P02] 衛生化学・公衆衛生学②

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