[28V11-pm] 消化管吸収

Sun. Mar 28, 2021 1:15 PM - 2:39 PM [Room V11] Oral Presentation 11 (Online)

座長：加藤将夫（⾦沢⼤院医薬保）、永井純也（大阪薬大）

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1:15 PM - 1:27 PM

[28V11-pm01] The mucosal barrier dysfunction of small intestine in ulcerative colitis model rats

○Makoto Ishii¹, Maho Kumagai¹, Rintaro Chiba¹, Yuka Nagasawa¹, Mikio Tomita¹ (1. Tohoku Med. and pharm. Univ.)

1:27 PM - 1:39 PM

[28V11-pm02] Regional defferences in intestinal barrier dysfunction through Claudin-4 expression level in Ulcerative colitis.

○Masahiko Mori¹, Maho Kumagai¹, Miyuki Hirata¹, Ayumi Sato¹, Makoto Isii¹, Mikio Tomita¹ (1. Tohoku Med and Pharm Univ.)

1:39 PM - 1:51 PM

[28V11-pm03S] A unique approach for oral administration of GLP-1 receptor agonist by using ionic liquids

○Takaya Sunami¹, Hidenori Ando¹, Atsuya Maruyama¹, Yasushi Miwa², Hidetoshi Hamamoto², Taro Shimizu¹, Yu Ishima¹, Tatsuhiro Ishida¹ (1. Grad. Sch. Biomed. Sci., Tokushima Univ., 2. MEDRx Co., Ltd.)

1:51 PM - 2:03 PM

[28V11-pm04S] Nano-crystalline solid dispersion of SH-683 with improved oral absorption

○Yuto Hayahi¹, Kenta Sasaki², Kouji Higuchi², Takeshi Shindo², Hiroshi Shigama², Kohei Yamada¹, Hideyuki Sato¹, Robert K. Prud'homme³, Satomi Onoue¹ (1. Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 2. Ishihara Sangyo Kaisha, Ltd., 3. Department of Chemical and Biological Engineering, Princeton University, USA)

2:03 PM - 2:15 PM

[28V11-pm05S] Design and biopharmaceutical evaluations of cyclosporine A-loaded solid lipid nanoparticles using PEGylated-lipids to control oral absorption

○Ryuya Terao¹, Asuka Nakazawa¹, Robert K. Prud'homme², Kohei Yamada¹, Hideyuki Sato¹, Satomi Onoue¹ (1. Lab. of Biopharmacy, Univ. of Shizuoka, 2. Princeton Univ.)

2:15 PM - 2:27 PM

[28V11-pm06S] Evaluation of physicochemical properties of compounds suitable for egg yolk lecithin-based emulsion

○Tatsuya Toriyama¹, Yuki Sato², Hitoshi Kashiwagi², Shungo Imai², Yoh Takekuma³, Mitsuru Sugawara^2,3 (1. Sch. Pharm. Sci. Pharm, Hokkaido Univ., 2. Fac. Pharm. Sci, Hokkaido Univ., 3. Dept. Pharm, Hokkaido Univ. Hosp.)

2:27 PM - 2:39 PM

[28V11-pm07S] Generation of Caco-2 cells expressing CYP3A4

○Michika Murata¹, Moe Ichikawa², Hiroki Akamine², Kazuo Takayama^1,2, Hiroyuki Mizuguchi^1,2,3,4,5 (1. School of Pharmaceutical Sci., Osaka Univ., 2. Grad. Sch. Pharmaceutical Sci., Osaka Univ., 3. The Center for Advanced Medical Engineering and Informatics, Osaka Univ., 4. Integrated Frontier Research for Medical Science Division, Institute for OTRI, Osaka Univ., 5. National Institutes of Biomedical Innovation, Health and Nutrition)

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