[28V11-pm] トランスポーター①/ADMET, PK/PD①

Sun. Mar 28, 2021 4:27 PM - 5:27 PM [Room V11] Oral Presentation 11 (Online)

座長：大槻純男（熊本大）、藤田卓也（立命館大薬）

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4:27 PM - 4:39 PM

[28V11-pm17S] RNA editing enzyme ADAR1 regulates the circadian expression of P-glycoprotein in human renal cells

○Yuji Omata¹, Tomoaki Yamauchi¹, Akito Tsuruta¹, Naoya Matsunaga¹, Satoru Koyanagi¹, Shigehiro Ohdo¹ (1. Grad. Sch. Pharm. Sci., Kyushu Univ.)

4:39 PM - 4:51 PM

[28V11-pm18S] The establishment of Caco-2 cells lacking MDR1 by CRISPR/Cas9 system to investigate drug-drug and drug-food interactions

○Akari Asano¹, Mutsuki Abe¹, Erika Mori¹, Ryohei Nasu¹, Midori Soda¹, Hironao Nakayama², Kiyoyuki Kitaichi¹ (1. Gifu Pharmaceutical Univ., 2. Hiroshima International Univ.)

4:51 PM - 5:03 PM

[28V11-pm19] Functional analysis of the extracellular aspartic acids conserved in hMCT1, 2, 4

○Atsushi Yamaguchi^1,2, Katsuya Narumi³, Ayako Furugen³, Ken Iseki³, Masaki Kobayashi³ (1. Dept. Pharm., Hokkaido Univ. Hosp., 2. Grad. Sch. Life. Sci., Hokkaido Univ., 3. Fac. Pharm. Sci., Hokkaido Unvi.)

5:03 PM - 5:15 PM

[28V11-pm20] Role of OATP4C1 in renal handling of remdesivir and its nucleoside analogue GS-441524: the first approved drug for patients with COVID-19

○Toshihiro Sato¹, Masamitsu Maekawa^1,2,3, Takaaki Abe^3,4, Hiroaki Yamaguchi^5,6, Nariyasu Mano^1,2,3 (1. Department of Pharmaceutical Sciences, Tohoku University Hospital, 2. Graduate School of Phamaceutical Sciences, Tohoku University, 3. Graduate School of Medicine, Tohoku University, 4. Graduate School of Biomedical Engineering, Tohoku University, 5. Department of Pharmacy, Yamagata University Hospital, 6. Graduate School of Medical Science, Yamagata University)

5:15 PM - 5:27 PM

[28V11-pm21S] Identification of Long-Circulating Extracellular Particles and Analysis of Their Pharmacokinetics

○Asahi Yoshida¹, Takuma Yamashita¹, Nozomi Otake¹, Yuki Takahashi¹, Yoshinobu Takakura¹ (1. Grad. Sch. Pharm Sci., Kyoto Univ.)

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