趣旨説明：清中 茂樹（名大院工） (9:30 AM - 9:33 AM)
Session information
Symposium
[S35] Frontier of photopharmacology for high-speed molecular movies of proteins
Mon. Mar 29, 2021 9:30 AM - 11:30 AM [Room E] Oral Presentation E (Online)
Organizer: Nagasawa Hideko (Gifu Pharm. Univ.), Kiyonaka Shigeki (Grad. Sch.Eng, Nagoya Univ.)
To understand the functions and regulatory mechanisms of proteins in detail, it is essential to track the chemical reactions and structural changes occurred in proteins with atomic resolution. Recently, utilization of X-ray free electron laser (XFEL) allowed us to visualize high-speed molecular movie which was triggered by photo-irradiation. However, light-activated proteins such as rhodopsin are very limited. Photopharmacological tools, which can control protein function by photo irradiation, are expected to overcome this limitation. The new chemical tools would be applied for visualizing high-speed molecular movie of various proteins. In this symposium, we will introduce recent progress on high-speed molecular movie of proteins using XFEL and newly developed photopharmacological methods. We will also discuss the possibility of photopharmacological tools as a new tool for controlling cellular functions.
9:33 AM - 9:52 AM
○Toru Nakatsu1 (1. Grad. Sch. Pharm. Sci., Kyoto Univ.)
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9:52 AM - 10:11 AM
○Takehiko Tosha1 (1. RIKEN SPring-8)
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10:11 AM - 10:30 AM
○Toshiaki Furuta1 (1. Fac. Sci., Toho Univ.)
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10:30 AM - 10:49 AM
○Shin Mizukami1 (1. Tohoku Univ, IMRAM)
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10:49 AM - 11:08 AM
○Kazuya Matsuo1 (1. RIES, Hokkaido Univ.)
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11:08 AM - 11:27 AM
○Tatsuyuki Yoshii1,2, Shinya Tsukiji1 (1. Grad. Sch. Eng., Nagoya Inst. Technol., 2. PRESTO, JST)
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総括：永澤 秀子（岐阜大薬） (11:27 AM - 11:30 AM)