[29V07-pm] ADMET, PK/PD②

Mon. Mar 29, 2021 1:15 PM - 3:15 PM [Room V07] Oral Presentation 7 (Online)

座長：伊藤清美（武蔵野大）、山下富義（京大院薬）

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1:15 PM - 1:27 PM

[29V07-pm01S] Establishment of analysis method for concentration of pemafibrate in biological samples and pharmacokinetic study using rats

○Atsushi Shigemura¹, Shinji Kobuchi¹, Yukako Ito¹, Toshiyuki Sakaeda¹ (1. Kyoto Pharm. Univ.)

1:27 PM - 1:39 PM

[29V07-pm02S] Effects of co-administration of statins on fibrate-induced adverse events

○Daisuke Sugiyama¹, Iori Yamasaki¹, Atsushi Shigemura¹, Shinji Kobuchi¹, Yukako Ito¹, Hikaru Ueda², Satoshi Yokoyama², Koichi Hosomi², Mitsutaka Takada², Toshiyuki Sakaeda¹ (1. Kyoto Pharm. Univ., 2. Kindai Univ.)

1:39 PM - 1:51 PM

[29V07-pm03S] Objective assessment of medication adherence and hypoglycemic effects of sodium-glucose cotransporter 2 inhibitor, dapagliflozin

○Kaede Kataoka¹, Naoya Matsuo¹, Shinji Kobuchi¹, Yukako Ito¹, Kenichiro Kato², Tetsuo Hayakawa², Toshiyuki Sakaeda¹ (1. Kyoto Pharm. Univ., 2. Tonami General Hosp. Diabetes/Endocrinology)

1:51 PM - 2:03 PM

[29V07-pm04S] Effect of diurnal variation on oxaliplatin distribution in dorsal root ganglion

○Shunta Ueda¹, Koubuchi Shinji¹, Ito Yukako¹, Nishida Kentaro², Sakaeda Toshiyuki¹ (1. Kyoto Pharma.Univ, 2. Setunan Univ)

2:03 PM - 2:15 PM

[29V07-pm05S] Management of colorectal cancer chemotherapy with chronic kidney disease based on population pharmacokinetic analysis in rats

○Ayane Yamamoto¹, Shinji Kobuchi¹, Yukako Ito¹, Toshiyuki Sakaeda¹ (1. Kyoto Pharm. Univ.)

2:15 PM - 2:27 PM

[29V07-pm06S] Pharmacokinetic-pharmacodynamic analysis of circulating tumor cells in mice treated with FOLFIRINOX regimen

○Mastui Yuki¹, Eriko Inoue¹, Yukako Ito¹, Shinji Kobuchi¹, Hayao Nakanishi², Toshiyuki Sakaeda¹ (1. Kyoto Pharm. Univ., 2. Nagoya Univ.)

2:27 PM - 2:39 PM

[29V07-pm07S] Optimization of Gas Vesicle (GV) preparation method and evaluation of pharmacokinetics of GV

○Takuma Yamaguchi¹, Takuma Koboya¹, Yuki Takahashi¹, Yoshinobu Takakura¹ (1. Grad. Sch. Pharm Sci., Kyoto Univ.)

2:39 PM - 2:51 PM

[29V07-pm08S] Evaluation of the effect of membrane-associated glycans on the pharmacokinetics of small extracellular vesicles

○Aki Yamamoto¹, Yukari Yasue¹, Yuki Takahashi¹, Yoshinobu Takakura¹ (1. Graduate School of Pharmaceutical Sciences, Kyoto University)

2:51 PM - 3:03 PM

[29V07-pm09S] Association of methotrexate-induced epithelial-mesenchymal transition with nuclear factor erythroid 2 like-2 in alveolar epithelial cells

○Mikito Honda², Takuya Hara¹, Ryoko Yumoto¹, Masashi Kawami¹, Mikihisa Takano¹ (1. Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 2. Sch. Pharm. Sci., Hiroshima Univ.)

3:03 PM - 3:15 PM

[29V07-pm10] Classification tree analysis based on machine learning for predicting linezolid-induced thrombocytopenia

○Saki Takahashi¹, Yasuhiro Tsuji², Hidefumi Kasai³, Chika Ogami¹, Hitoshi Kawasuji⁴, Yoshihiro Yamamoto⁴, Hideto To¹ (1. Sch. Pharm. Sci., Toyama Univ., 2. Sch. Pharm., Nihon Univ., 3. Keio Univ. Sch. Med., 4. Grad. Sch. Med. Pharm. Sci., Toyama Univ.)

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