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○Tatsuya Inui¹, Tomoki Yamasita¹, Ryuga Nomoto¹, Jumpei Yokota¹, Kentaro Kawakami^2,3, Wataru Kishimoto⁵, Hiroshi Nakase², Hiroyuki Mizuguchi^1,4,6,7 (1. Grad. Sch. of Pharm. Sci, Osaka Univ., 2. Sch. of Med., Sapporo Med. Univ., 3. Keiyukai Sapporo Hosp., 4. NIBIOHN, 5. Nippon Boehringer Ingelheim Co., Ltd., 6. MEI cent., Osaka Univ., 7. OTRI, Osaka Univ.)