[29-413-pm] Drug design 1

Fri. Mar 29, 2024 1:15 PM - 2:15 PM [Room 413] Conference Center 413 (4F)

Chair: Baba Yoshiyasu, Tetsuta Oshitari

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1:15 PM - 1:27 PM

[29-413-pm01S] Effect of modification pattern of gapmer antisense oligonucleotides on off-target toxicity

○Chihiro Oda^1,2, Yuuya Kasahara^1,2, Harumi Yamaguma², Satoshi Obika^1,3 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. NIBIOHN, 3. OTRI, Osaka Univ.)

1:27 PM - 1:39 PM

[29-413-pm02] Design of antisense oligonucleotides targeting a host factor for antiviral drug development

○Yuuya Kasahara¹, Tokiko Watanabe^2,3,4, Natsumi Kameoka¹, Harumi Yamaguma¹, Itsuki Anzai^2,3, Hina Miyazaki², Kosuke Takada², Yurie Kida², Satoshi Obika^3,4,5,6 (1. NIBIOHN, 2. RIMD, Osaka Univ., 3. CiDER, 4. CAMaD, 5. Grad. Sch. Pharm. Sci., Osaka Univ., 6. OTRI, Osaka Univ.)

1:39 PM - 1:51 PM

[29-413-pm03S] Structure-activity relationship (SAR) study of hydrophobic moiety of nonsecosteroidal VDR ligands using diphenylsilane scaffold

○Hansaka Nirupama Thilakarathne Narasinghe Mudiyanselage^1,2, Takashi Misawa³, Yosuke Demizu³, Yuya Hanazono², Nobutoshi Ito², Hiroyuki Kagechika¹, Shinya Fujii¹ (1. Institute of Biomaterials and Bioengineering, Tokyo medical and Dental University, 2. Medical Research Institute, Tokyo Medical and Dental University, 3. National Institute of Health Sciences)

1:51 PM - 2:03 PM

[29-413-pm04S] Physicochemical property and estrogenic activity of B-(hydroxyphenyl) phosphine borane derivatives

○Yu Miyajima¹, Tomomi Noguchi-Yachide², Hiroyuki Kagechika¹, Shinya Fujii¹ (1. IBB, Tokyo Medical and Dental Univ., 2. IQB, The Univ. of Tokyo)

2:03 PM - 2:15 PM

[29-413-pm05S] Development of novel XIAP inhibitors by using peptidomimetics

○Koutaro Sasaki¹, Ruka Ito², Yuria Kuwana², Kouji Kuramochi³, Atsushi Yoshimori⁴, Ryoko Takasawa^1,2 (1. Dept. Pharm. Sci., Grad. Sch. Pharm. Sci., Tokyo Univ. Sci., 2. Facul. Pharm. Sci., Tokyo Univ. Sci., 3. Facul. Sci. Tech., Tokyo Univ. Sci., 4. ITM, Inc.)

Session information