Resemblance of Binding Cavity Conformation in Bleg1_2478 to B3 Subclass of Metallo-β-Lactamase and Glyoxalase II Allows Accommodation of Ampicillin and S-D-Lactoylglutathione (C000103)

Shaw Xian Au

3:20 PM - 3:30 PM

[B-O2-02] Resemblance of Binding Cavity Conformation in Bleg1_2478 to B3 Subclass of Metallo-β-Lactamase and Glyoxalase II Allows Accommodation of Ampicillin and S-D-Lactoylglutathione (C000103)

*Shaw Xian Au^1,2, Noor Dina Muhd Noor^1,3, Hiroyoshi Matsumura⁴, Raja Noor Zaliha Raja Abdul Rahman^1,5, Normi Mohd Yahaya^1,2 (1. EMTech Research Center, Fac. of Biotechnology and Biomolecular Sciences, Univ. Putra Malaysia, Malaysia, 2. Dept. of Cell and Molecular Biology, Fac. of Biotechnology and Biomolecular Sciences, Univ. Putra Malaysia, Malaysia, 3. Dept. of Biochemistry, Fac. of Biotechnology and Biomolecular Sciences, Univ. Putra Malaysia, Malaysia, 4. College of Life Sciences, Ritsumeikan Univ., Japan, 5. Dept. of Microbiology, Fac. of Biotechnology and Biomolecular Sciences, Univ. Putra Malaysia, Malaysia)

Keywords:Bleg1_2478, metallo-β-lactamase, glyoxalase II, substrate binding, molecular docking

Presentation information

Biological Sciences Session 2

[B-O2-02] Resemblance of Binding Cavity Conformation in Bleg1_2478 to B3 Subclass of Metallo-β-Lactamase and Glyoxalase II Allows Accommodation of Ampicillin and S-D-Lactoylglutathione (C000103)