The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[1P0170] The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis

〇Akira Sato1, Hisako Kayama2, Kensaku Shojima1, Shinji Matsumoto1, Hirofumi Koyama1, Yasuhiro Minami3, Satoshi Nojima4, Eiichi Morii4, Hiroaki Honda5, Kiyoshi Takeda2, Akira Kikuchi1 (1.Dept. Mol. Biol. and Biochem., Grad. Sch. Med., Osaka Univ., 2.Dept. Micro. Immunol., Grad. Sch. Med., Osaka Univ., 3.Dept. Physiol. and Cell Biol., Grad. Sch. Med., Kobe Univ., 4.Dept. Pathol., Grad. Sch. Med., Osaka Univ., 5.Dept. Disease Model, Res. Inst. Radiation Biol. and Med., Hiroshima Univ.)

the Wnt5a-Ror2 axis, the Wnt/β-catenin independent pathway, colitis, dendritic cell, Th1 polarization

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