4:45 PM - 6:45 PM

[1P0174] Spermidine and Ca2+, but not Na+, can permeate NMDA receptors in the presence of Mg2+

Tadao Hirose¹, 〇Kyohei Higashi¹, Ryotaro Saiki^1,2, Yuki Yoshizawa¹, Masataka Imamura¹, Itsuko Ishii¹, Toshihiko Toida¹, Keith Williams³, Keiko Kashiwagi⁴, Kazuei Igarashi^1,2 (1.Grad. Sch. of Pharm. Sci., Chiba Univ., 2.Amine Pharma Res. Inst., 3.State Univ. of New York Downstate Medical Center, 4.Fac. of Pharm., Chiba Inst. of Sci.)

NMDA receptor, Spermidine influx, Ca2+ influx, Inhibition of Na+ influx by Mg2+