The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[1P0175] Enzymatic production of polysulfides and their function of activating TRPA1 channels in rat brain

〇Yuka Kimura1, Yoshinori Mikami2, Kimiko Osumi1, Mamiko Tsugane3, Jun-ichiro Oka4, Yukiko Toyofuku1, Shin Koike1,5, Norihiro Shibuya1, Noriyuki Nagahara6, Yuki Ogasawara5, Hideo Kimura1 (1.Dept. of Mol. Pharmacol., Natl. Inst. Neurosci., NCNP, 2.Dept. of Cell. Mol. Pharmacol., Grad. Sch. Med., Univ. of Tokyo, 3.Fcalty. Sci., Eng., Chuo Univ., 4.Dept. Pharmacy, Tokyo Univ. of Sci., 5.Dept. Anal. Biochem, Meiji Pharm. Univ., 6.Radioisotope center, Nippon Med. Sch.)

polysulfide, hydrogen sulfide, astrocyte, TRPA1, 3-mercaptopyruvate sulfurtransferase (3MST)

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