The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[1P0649] Cells irradiated by gamma-ray accumulate irrepairable DSBs during subsequent DNA replication after massive DSB repair.

〇Yusuke Minakawa1,2, Yuko Atsumi1,3, Yasufumi Murakami2, Hitoshi Nakagama1, Ken-ichi Yoshioka1 (1.Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 2.Biological Science and Technology, Tokyo University of Science, 3.Department of Biosciences, School of Science, Kitasato University)

DNA repair, H2AX, DNA replication stress, senescence

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