4:45 PM - 6:45 PM

[1P0888] cHS4 and a Ubiquitous Chromatin Opening Element Support Transgene Expression From Herpes Simplex Virus Vectors in the Absence of Immediate-Early Gene Expression

〇Yoshitaka Miyagawa², Fang Han^1,2, Gianluca Verlengia³, Michele Simonato³, Justus B. Cohen², Joseph C. Glorioso² (1.School of Medicine, Tsinghua University, P.R. China, 2.Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, USA, 3.Section of Pharmacology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy)

Herpes simplex virus, Gene therapy, A2UCOE, cHS4, transgene