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[1P1155] Metachromin A, a sesquiterpene purified from marine sponge, inhibits activity of hepatitis B virus core promoter, leading to antiviral effect.

〇Atsuya Yamashita1, Tomohisa Tanaka1, Kaori Dobashi1, Hirotake Kasai1, Koichi Watashi2, Takaji Wakita2, Masaaki Toyama3, Masanori Baba3, Shinya Maekawa4, Nobuyuki Enomoto4, Mayumi Tamaki5, Junichi Tanaka5, Kohji Moriishi1 (1.Dept. of Microbio., Grad. Sch. of Med., Univ. of Yamanashi, 2.Dept. of Virol II, Natl. Inst. of Infect.Dis., 3.Div. of Antiviral chemother., Grad. Sch. Of Med.& Dent., Univ. of kagoshima, 4.1st Dept. of Intern. Med., Grad. Sch. of Med., Univ. of Yamanashi, 5.Fac..of Sci., Univ. of Ryukyus)

HBV

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