2:20 PM - 2:30 PM

[1T25p-03(1P0583)] Cell-Based Screen for Altered Nuclear Phenotypes Reveals Senescence Progression in Polyploid Cells

〇Mahito Sadaie^1,2, Christian Dillon³, Masako Narita¹, Andrew R.J. Young¹, Claire J. Cairney⁴, Lauren S. Godwin⁵, Christopher J. Torrance⁶, Dorothy C. Bennett⁵, W. Nicol Keith⁴, Masashi Narita¹ (1.CRUK, CI, Univ. of Cambridge, 2.Lab. of Cell Cycle Regulation, Grad. Sch. of Biostudies, Univ. of Kyoto, 3.CRT, DL, 4.ICS, WWCRC, Univ. of Glasgow, 5.St. George's, Univ. of London, 6.Horizon Discovery Ltd)

Cellular Senescence, Cancer Therapy, Aurora Kinase B, Senescence-Associated Heterochromatic Foci (SAHF)