The Japanese Biochemical Society/The Molecular Biology Society of Japan

BMB2015 Biochemistry and Molecular Biology

BMB2015 Biochemistry and Molecular Biology

Dec 1, 2015 - Dec 4, 2015
Kobe Port Island

10:10 AM - 10:20 AM

[2T特-08(2P0325)] Development of modified human beta-Hexosaminidase B and evaluation of therapeutic effects on GM2 gangliosidosis model mice

〇Keisuke Kitakaze1, Yasumichi Mizutani1, Eiji Sugiyama2, Nobuo Maita3, Takatsugu Hirokawa4, Mitsutoshi Setou2, Hitoshi Sakuraba5, Kohji Itoh1 (1.Dept. of Med. Biotech., Inst. for Med. Res., Grad. Sch. of Pharm. Sci., Tokushima Univ., 2.Dept. of Cell Biol. and Anat., Hamamatsu Univ. Sch. of Med., 3.Lab. of X-ray Crystallography, Inst. for Enzyme Res., Tokushima Univ, 4.Molprof, AIST, 5.Dept. of Clin. Genetics, Meiji Pharm. Univ.)

lysosome, glycolipid, ganglioside, neurodegenerative disease, imaging mass spectrometry

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