The Japanese Biochemical Society/The Molecular Biology Society of Japan

BMB2015 Biochemistry and Molecular Biology

BMB2015 Biochemistry and Molecular Biology

Dec 1, 2015 - Dec 4, 2015
Kobe Port Island

4:45 PM - 6:45 PM

[3P0269] Gene disruption of GlcNAc 6-O-sulfotransferase-1 results in loss of microglial keratan sulfate and alleviation of Alzheimer's pathogenesis in mice

〇Zui Zhang1, Yoshiko Uchimura-Takeda1, Tahmina Foyez1, Shiori Niimi-Ohtake1, Hitomi Hoshino2, Tomomi Hosono-Fukao3, Makoto Michikawa4, Kenji Kadomatsu1, Kenji Uchimura1 (1.Dept of Biochem, Nagoya Univ Grad Sch of Med, 2.Dept of Pathol, Fukui Univ Grad Sch of Med, 3.Human Life, Env Sci, Ochanomizu Univ, 4.Dept of Biochem, Nagoya City Univ Grad Sch of Med)

sulfotransferase, keratan sulfate, microglia, Alzheimer's disease, neurodegeneration

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