16:45 〜 18:45

[3P0269] Gene disruption of GlcNAc 6-O-sulfotransferase-1 results in loss of microglial keratan sulfate and alleviation of Alzheimer's pathogenesis in mice

〇張 酔¹、内村-武田 佳子¹、Tahmina Foyez¹、新美-大竹 しおり¹、星野 瞳²、細野-深尾 友美³、道川 誠⁴、門松 健治¹、内村 健治¹ (1.名大・院医・一生化、2.福井大・院医・病理、3.お茶の水大・生活科学、4.名市大・院医・生化)

sulfotransferase, keratan sulfate, microglia, Alzheimer's disease, neurodegeneration