4:45 PM - 6:45 PM

[3P0321(3T17-10)] X-ray crystal structure analysis of Acetyl-CoA synthetase, the key enzyme in acetate and lipid metabolism, of Trypanosoma brucei

〇Shigeo Suzuki¹, Daniel K Inaoka¹, Emmanuel O. Balogun¹, Adriane Pauluk², Josmar R. Rocha², Tomoo Shiba³, Shigeharu Harada³, Frederic Bringaud⁴, Kiyoshi Kita¹ (1.Dept. of Biomed. Chem., Grad. Sch. of Med., Univ. of Tokyo, 2.Inst. of Chem. of Sao Carlos, Univ. of Sao Paulo, 3.Dept. of Appl. Biol., Kyoto Inst. of Tech., 4.Cent. of Reson. Magnet. of Sys. Biol., Univ. of Bordeaux Segalen)

acetate fermentation, lipid metabolism, acetyl-CoA synthetase (AceCS), crystal structure, neglected tropical diseases (NTDs)