The Japanese Biochemical Society/The Molecular Biology Society of Japan

BMB2015 Biochemistry and Molecular Biology

BMB2015 Biochemistry and Molecular Biology

Dec 1, 2015 - Dec 4, 2015
Kobe Port Island

4:45 PM - 6:45 PM

[3P0701(4T14L-01)] A Mediator subunit MED16 transduces NRF2-activating electrophilic signals into antioxidant gene expression

〇Keito Okazaki1, Hiroki Sekine1, Norio Suzuki2, Yasutake Katoh3, Kazuhiko Igarashi4, Mitsuhiro Ito5, Hozumi Motohashi1, Masayuki Yamamoto2,3 (1.Dept. of Gene Exp. Reg., Inst. of Dev., Aging and Cancer, Tohoku Univ., 2.Dept. of Med. Biochem., Tohoku Univ. Grad. Sch. of Med., 3.Tohoku Med., Megabank Org., Tohoku Univ., 4.Dept. of Biochem., Tohoku Univ. Grad. Sch. of Med., 5.Labo. of Hematology, Div. of Med. Biophysics, Kobe Univ. Grad. Sch. of Health Sciences)

NRF2, mediator complex, transcriptional regulation, oxidative stress

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