The Japanese Biochemical Society/The Molecular Biology Society of Japan

4:45 PM - 6:45 PM

[3P1071(4T18-09)] CD74-NRG1, a fusion gene product, leads to ErbB-NFĸB-IGF2 autocrine/paracrine circuit and confers cancer stem cell properties

〇Takahiko Murayama1,2,3, Takashi Nakaoku4, Masato Enari5, Tatsunori Nishimura1, Kana Tominaga3, Asuka Nakata1, Arinobu Tojo3, Sumio Sugano2, Takashi Kohno4, Gotoh Noriko1,3 (1.Div. Cancer Cell Biol., Cancer Res. Inst. Kanazawa Univ., 2.Lab. Functional Genomics, Grad. Sch. Frontier Sci., Univ. Tokyo, 3.Div. Mol. Therapy, IMS, Univ. Tokyo, 4.Div. Genome Biol., Natl. Cancer Ctr. Res. Inst., 5.Div. Refractory Cancer Res., Natl. Cancer Ctr. Res. Inst.)

cancer stem cell, fusion gene

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