The Japanese Biochemical Society/The Molecular Biology Society of Japan

4:45 PM - 6:45 PM

[3P1187(4T特-11)] MML-1/Mondo complexes regulate HLH-30/TFEB via TOR inhibition to promote longevity in response to signals from the reproductive system

〇Shuhei Nakamura1, Oezlem Karalay1, Philipp S. Jaeger1, Makoto Horikawa1, Corinna Klein4, Kayo Nakamura1, Christian Latza1, Sven E. Templer4, Christoph Dieterich4, Adam Antebi1,2,3 (1.Dept. Molecular Genetics of Ageing, Max Planck Institute for Biology of Ageing, 2.Dept. of Molecular and Cellular Biology, Huffington Center on Aging, Baylor College of Medicine, 3.Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Univ. of Cologne, 4.Bioinformatics Core Facility, Max Planck Institute for Biology of Ageing)

Mondo, longevity, C. elegans, autophagy, TFEB

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