4:45 PM - 6:45 PM

[3P1203(4T特L-12)] Activation of hepatic hypoxia-inducible factor 1α promotes formation of cholesterol gallstones

〇Yoichiro Asai¹, Tetsuya Yamada¹, Sohei Tsukita¹, Kei Takahashi¹, Masamitsu Maekawa², Midori Honma¹, Yuichiro Munakata¹, Yuta Shirai¹, Shinjiro Kodama¹, Takashi Sugisawa¹, Yumiko Chiba¹, Hironobu Takahashi¹, Shinichiro Hosaka¹, Yasuteru Kondo³, Keizo Kaneko¹, Kenji Uno¹, Shojiro Sawada¹, Junta Imai¹, Yasuhiro Nakamura⁴, Hiroaki Yamaguchi², Yoshitomo Oka¹, Hironobu Sasano⁴, Nariyasu Mano², Yoshiyuki Ueno⁵, Tooru Shimosegawa³, Hideki Katagiri^1,6 (1.Dept. of Metab., Grad. Sch. of Med., Tohoku Univ., 2.Dept. of Pharma., Tohoku Univ. Hosp., 3.Dept. of Gastro., Grad. Sch. of Med., Tohoku Univ., 4.Dept. of Pathol., Grad. Sch. of Med., Tohoku Univ., 5.Dept. of Gastro., Fac. of Med., Yamagata Univ., 6.Jap. Sci. and Tech. Agen., CREST)

hypoxia, HIF-1α, liver steatosis, gallstone, aquaporin