The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[3P1253] Novel small molecules identified by in silico screening induce TrkB activation and decrease depression-like behavior in mice

〇Mayu Fukuda1,4, Atsushi Takatori1,2, Yohko Nakamura1,3, Akiko Suganami5, Tyuji Hoshino6, Yutaka Tamura5, Akira Nakagawara7, Masatoshi Tagawa8 (1.Div. of Innovative Cancer Therapeutics, Chiba Cancer Ctr. Res. Inst., 2.Div. of Cancer Genetics, Chiba Cancer Ctr. Res. Inst., 3.Div. of Cancer Prevention and Epidemiology, Chiba Cancer Ctr. Res. Inst., 4.Grad. Sch. of Med. and Pharmaceutical Sciences, Chiba Univ., 5.Dept. of Bioinformatics, Grad. Sch. of Med., Chiba Univ., 6.Grad. Sch. of Pharmaceutical Sciences, Chiba Univ., 7.Saga Medical Ctr. KOSEIKAN, 8.Div. of Cell Therapy, Chiba Cancer Ctr. Res. Inst.)

TrkB, BDNF, Depression

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