The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[3W6-6] The class III phosphoinositide 3-kinase Vps34 plays a critical role in human cardiac hypertrophy by regulating degradation of proteins via ESCRT.

〇Hirotaka Kimura1,2, Satoshi Eguchi1, Keiji Kuba3, Yumiko Imai4, Shunsuke Takasuga1, Reietsu Itoh1, Ryohtaro Nakamura1, Hiroki Nakanishi2, Masaki Ishikawa1, Junko Sasaki1, Masakazu Yamazaki5, Takehiko Sasaki1,2 (1.Dept. of Med. biol., Akita Univ.Grad.Sch.of Medicine, 2.Research center of biosignal, Akita Univ., 3.Dept. of Biochem. Metabolic Science, Akita Univ.Grad.Sch.of Medicine, 4.Dept. of Biol. inform. Exp. therap., Akita Univ.Grad.Sch.of Medicine, 5.Dept. of Cell Biol. morphology, Akita Univ.Grad.Sch.of Medicine)

Vps34, Cardiac Hypertrophy, ESCRT

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