The Japanese Biochemical Society/The Molecular Biology Society of Japan

3:10 PM - 3:20 PM

[4T18p-08(3P1264)] WDR62/MCPH2 mutations identified in patients with primary microcephaly disrupt mitotic spindle orientation axis

〇Yoshinori Masatsuna1, Silvia Natsuko Akutsu1, Kosuke Hosoba1, Hiroyuki Morino2, Hideshi Kawakami2, Takashi Tamamoto3, Kenji Shimizu4, Hirofumi Oohashi4, Tatsuo Miyamoto1, Shinya Matsuura1 (1.Dept. Genet & Cell Biol., RIRBM, Hiroshima Univ., 2.Dept. Epidemiol., RIRBM, Hiroshima Univ., 3.Dept. of Math. and Life. Sci., Grad. Sch. of Sci. Hiroshima Univ., 4.Dept. Genet., Saitama Children's Medical Center.)

microcephaly, centrosome, whole exome sequencing, genome editing

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