The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[4T特L-12(3P1203)] Activation of hepatic hypoxia-inducible factor 1α promotes formation of cholesterol gallstones

〇Yoichiro Asai1, Tetsuya Yamada1, Sohei Tsukita1, Kei Takahashi1, Masamitsu Maekawa2, Midori Honma1, Yuichiro Munakata1, Yuta Shirai1, Shinjiro Kodama1, Takashi Sugisawa1, Yumiko Chiba1, Hironobu Takahashi1, Shinichiro Hosaka1, Yasuteru Kondo3, Keizo Kaneko1, Kenji Uno1, Shojiro Sawada1, Junta Imai1, Yasuhiro Nakamura4, Hiroaki Yamaguchi2, Yoshitomo Oka1, Hironobu Sasano4, Nariyasu Mano2, Yoshiyuki Ueno5, Tooru Shimosegawa3, Hideki Katagiri1,6 (1.Dept. of Metab., Grad. Sch. of Med., Tohoku Univ., 2.Dept. of Pharma., Tohoku Univ. Hosp., 3.Dept. of Gastro., Grad. Sch. of Med., Tohoku Univ., 4.Dept. of Pathol., Grad. Sch. of Med., Tohoku Univ., 5.Dept. of Gastro., Fac. of Med., Yamagata Univ., 6.Jap. Sci. and Tech. Agen., CREST)

hypoxia, HIF-1α, liver steatosis, gallstone, aquaporin

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