1:45 PM - 1:55 PM

[4T特L-13(3P1204)] Sdf2l1/XBP-1s axis controls glucose and lipid homeostasis through regulation of physiologic endoplasmic reticulum stress induced by feeding in the liver

〇Takayoshi Sasako^1,2,3, Kenichiro Enooku⁴, Naoto Kubota^1,2, Kazuhiko Koike⁴, Takashi Kadowaki^1,2, Kohjiro Ueki^1,2,3,5 (1.Translational Systems Biol. and Med. Initiative (TSBMI), Univ. of Tokyo, 2.Dept. of Diabetes and Metabolic Diseases, Grad. Sch. of Med. , Univ. of Tokyo, 3.Dept. of Molecular Diabetic Med., Diabetes Res. Center, National Center for Global Health and Med., 4.Dept. of Gastroenterology, Grad. Sch. of Med. , Univ. of Tokyo, 5.Dept. of Molecular Sci. on Diabetes, Grad. Sch. of Med. , Univ. of Tokyo)

insulin resistance, endoplasmic reticulum stress, nonalcoholic steatohepatitis