The Japanese Biochemical Society/The Molecular Biology Society of Japan

BMB2015 Biochemistry and Molecular Biology

BMB2015 Biochemistry and Molecular Biology

Dec 1, 2015 - Dec 4, 2015
Kobe Port Island

9:25 AM - 9:45 AM

[4W13-2] Bisecting GlcNAc modification of BACE1 promotes development of Alzheimer's disease

〇Yasuhiko Kizuka1, Shinobu Kitazume1, Miyako Nakano2, Takaomi C. Saido3, Yasuhiro Hashimoto4, Tamao Endo5, Naoyuki Taniguchi1 (1.Disease Glycomics Team, RIKEN, 2.Grad. Sch. of Adv. Sci. Matter, Hiroshima Univ., 3.Proteolytic Neurosci., RIKEN, 4.Dept. of Biochem., Fukushima Med., Univ., 5.Tokyo Metro. Geriatric Inst.)

Alzheimer's disease, BACE1, GnT-III, bisecting GlcNAc, glycosylation

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