[3P0655(3T25p-11)] Novel 53BP1 binding protein SCAI facilitates homologous recombination through Rif1 inhibition

〇Shinya Isobe¹, Yoshinobu Okubo¹, Shohei Ishimoto¹, Koji Nagao¹, Naohito Nozaki², Hiroshi Kimura³, Chikashi Obuse¹ (1.Grad. Sch. of Life Sci., Hokkaido Univ., 2.MAB Institute Incorporated, 3.Grad. Sch. of Biosci. and Biotech., Tokyo Ins. Tech.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0656(3T25p-12)] The synaptonemal complex regulates meiotic recombination

〇Wataru Kobayashi¹, Motoki Takaku¹, Mutsumi Teramoto¹, Shinichi Machida¹, Hiroaki Tachiwana¹, Noriko Hosoya², Kiyoshi Miyagawa², Kazumitsu Maehara³, Yasuyuki Ohkawa³, Hitoshi Kurumizaka¹ (1.Grad. Sch. of Adv. Sci. and Eng., Waseda Univ./RISE, 2.Lab. of Mol. Radiol., CDBIM, Grad. Sch. of Med., Univ. of Tokyo, 3.Grad. Sch. of Med., Kyushu Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0657(3T25p-13)] The synaptonemal complex protein SYCE2 affects the function of the heterochromatin proteins and promotes DNA double-strand break repair

〇Noriko Hosoya¹, Masato Ono¹, Kiyoshi Miyagawa¹ (1.Lab. of Mol. Radiol., Grad. Sch. of Med., The Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0658(3T25p-14)] ATM and DNA-PKcs suppress pairing between multiple DNA double-strand breaks

〇Motohiro Yamauchi¹, Keiji Suzuki², Atsushi Shibata³, Atsuko Niimi⁴, Masatoshi Suzuki⁵, Hisayoshi Kondo⁶, Miwa Miura⁷, Miyako Hirakawa¹, Shunichi Yamashita², Naoki Matsuda¹ (1.Dept. Radiat. Biol. Protect., A. Bomb Disease Inst., Nagasaki Univ., 2.Dept. Radiat. Med. Sci., A. Bomb Disease Inst., Nagasaki Univ., 3.Adv. Sci. Res. Leaders Dev. Unit, Gunma Univ., 4.Gunma Univ. Initiat. Adv. Res., 5.Dept. Pathol., Inst. Dev. Aging Cancer, Tohoku Univ., 6.Dept. Global Health Med. Welfare, A. Bomb Disease Inst., Nagasaki Univ., 7.Center Front. Life Sci., Nagasaki Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0659(3T25p-15)] Distinct DNA damage spectra induced by ionizing radiation in normoxic and hypoxic cells

〇Masato Ooka¹, Naoto Shimizu¹, Tokiyo Takagi¹, shunichi Takeda², Kouji Hirota¹ (1.Dept. of Chem., Grad. Sch. of Sci and Engi., Tokyo Metropol Univ., 2.Dept. of Radi Genet, Grad. Sch. of Medi., Kyoto Univ)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0660(4T27L-01)] Impacts of shRNA-mediated Ku70 gene suppression and radiation exposure on mitosis

〇Yasutomo Yutoku¹, Aki Koike², Manabu Koike¹ (1.NIRS, 2.NIRS)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0661(4T27L-02)] Regulation of UV-induced DNA damage response and repair by the ubiquitin-proteasome system

〇Wataru Sakai^1,2, Aiko Kishimoto^1,2, Takeshi Matsui^1,2, Yuuki Kaneko^1,2, Jun-ichi Akagi¹, Kaoru Sugasawa^1,2 (1.Biosignal Res. Ctr., Kobe Univ., 2.Grad. Sch. Sci., Kobe Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0662(4T27L-03)] Identification of ubiquitination factor as a key regulator of Top2-poison response

〇Ryo Sakasai¹, Yumi Sunatani¹, Tadashi Matsui¹, Mitsumasa Hashimoto², Kuniyoshi Iwabuchi¹ (1.Dept. of Biochem. I., Kanazawa Med. Univ., 2.Dept. of Physics, Kanazawa Med. Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0663(4T27L-04)] Immunoglobulin gene diversification by activation-induced cytidine deaminase (AID) through Topoisomerase1 (Top1)

〇Maki Kobayashi¹, Hiroyuki Wakaguri², Masakazu Shimizu², Koh-ichiro Higasa², Fumihiko Matsuda², Tasuku Honjo¹ (1.Dept. of Immunol. Genomic Med., Kyoto Univ., 2.Ctr. for Genomic Med., Kyoto Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P0664(4T27L-05)] Antigen receptor gene assembly in hagfish

〇Fumikiyo Nagawa¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM