The Japanese Biochemical Society/The Molecular Biology Society of Japan

6675 results (6021 - 6030)

[3P1112] Anti-tumor efficacy and preferential localization of KR12, KRAS mutation specific alkylating agent in KRAS mutant xenografts with little to no adverse effects

〇Takahiro Inoue1, Kiriko Hiraoka1, Hiroyuki Yoda1, Takayoshi Watanabe1, Atsushi Takatori1, Nobuko Koshikawa1, Shigeharu Wakana3, Toshikazu Bando4, Hiroshi Sugiyama4, Toshinori Ozaki2, Hiroki Nagase1 (1.Lab. Cancer Genetics, Chiba Cancer Centr. Res. Inst., 2.Lab. DNA Damage Signaling, Chiba Cancer Centr Res. Inst., 3.Japan Mouse Clinic, RIKEN BRC, 4.Dep. Chem., Grad. Sch. Sci., Univ. Kyoto)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1115] Is transglutaminase 2 (TGM2), a proteomics marker of early recurrence of hepatocellular carcinoma, related to EMT activation?

〇Hiromi Yamaguchi1, Kazumichi Kuroda2, Yukari Hirotani1, Masahiko Sugitani1, Kiyoshi Hasegawa3, Tadatoshi Takayama4, Mariko Esumi1 (1.Dept. of Pathol., Nihon Univ. Sch. of Med., 2.Div. Microbiol., Nihon Univ. Sch. of Med., 3.Dept. Hepatobil. Surg., Fac. Med., Univ. of Tokyo, 4.Div. Dig. Surg., Dept. Surg., Nihon Univ. Sch. of Med.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1117] Elevated β-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs

〇Asuka Nakata1, Ryo Yoshida2, Rui Yamaguchi3, Yoshinori Tamada4, Andre Fujita4, Teppei Shimamura4, Seiya Imoto4, Tomoyuki Higuchi2, Masaharu Nomura5, Tatsuo Kimura6, Hiroshi Nokihara7, Masahiko Higashiyama8, Kazuya Kondoh9, Hiroshi Nishihara10, Arinobu Tojo11, Seiji Yano12, Satoru Miyano3,4, Noriko Gotoh1 (1.Div. of Cancer Cell Biol., Cancer Res. Inst., Kanazawa Univ., 2.Inst. of Statistical Mathematics, 3.Sequence Analysis, Inst. of Med. Sci., Univ. of Tokyo, 4.DNA information Analysis, Inst. of Med. Sci., Univ. of Tokyo, 5.Hosp. 1st. Dept. of Surg., Tokyo Med. Univ., 6.Osaka City Univ., 7.Natl. Cancer Ctr. Hosp., 8.Osaka Medical Center for Cancer and Cardiovascular Diseases, 9.The Univ. of Tokushima Grad. Sch., 10.Hokkaido Univ. Grad. Sch. of Med., 11.Div. of Mol. Therapy, Inst. of Med. Sci., Univ. of Tokyo, 12.Div. of Med. Oncol., Cancer Res. Inst., Kanazawa Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1118] Identification and functional analysis of a novel Akt repressor p53PAD9

〇Mayuna Shimada1,2, Yuhei Takano1,3, Tatsuya Kawase4, Kentaro Semba2,3,5, Rieko Ohki1 (1.Div. of Rare Cancer Res., Natl. Cancer Ctr. Res. Inst., 2.Dept. of Life Sci. and Med. BioSci, Grad. Sch. of Sci. and Eng., Waseda Univ., 3.Dept. of Life Sci. and Med. BioSci, Grad. Sch. of Sci. and Eng., Waseda Univ., 4.Div. of Radiobiology, Natl. Cancer Ctr. Res. Inst., 5.Translational Res. Ctr., Fukushima Med. Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

6675 results (6021 - 6030)