The Japanese Biochemical Society/The Molecular Biology Society of Japan

10:50 AM - 11:00 AM

[1AT26-12(1P-0061)] The additional deletion of Engase can partially rescue the defects caused by Ngly1 deletion

〇Haruhiko Fujihira1,2, Yuki Negishi-Masahara1, Masaru Tamura3, Daisuke Takakura4,5, Chengcheng Huang1, Shigeharu Wakana3, Nana Kawasaki4, Yoko Funakoshi1, Tadashi Suzuki1 (1.Glycometabolome Team, Global Research Cluster, RIKEN, 2.Div. of Glycobiologics, Intractable Dis. Res. Center, Juntendo Univ. Graduate Sch. of Med., 3.Technol. and Devel. Team for Mouse Phenotype Anal., BRC, RIKEN, 4.Lab. of Biopharmaceut. and Regenerative, Graduate Sch. of Med. Life, Yokohama City Univ., 5.Center for Integrated Med. Res., Keio Univ.)

Peptide:N-glycanase (Ngly1)、Endo-beta-N-acetylglucosaminidase (ENGase)、NGLY1-deficiency、protein degradation system

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