[1LBA-040] Genetic Analysis of Pathogenic Germline Mutations in Japanese Patients with Suspected Lynch Syndrome

〇Sariya Dechamethakun^1,2、Hidetaka Eguchi^1,2、Yuhki Tada^2,3、Tomoko Hirata²、Masakazu Kohda^1,2、Kosei Hasegawa⁴、Shinji Ohki⁵、Kiwamu Akagi⁶、Naohiro Tomita⁷、Kohji Tanakaya⁸、Tatsuro Yamaguchi⁹、Hideyuki Ishida¹⁰、Yasushi Okazaki ^1,2 (1.Intractable Disease Res. Ctr., Grad. Sch. of Med., Juntendo Univ.、2.Div. of Translat. Res., Res. Ctr. for Genom. Med., Saitama Med. Univ.、3.Tech. & Develop. Team for Mammal. Genome Dynamics, RIKEN BioResource Ctr.、4.Dept. of Gynecol. Oncol., Saitama Med. Univ. Intl. Med. Ctr. 、5.Dept. of Organ Regulatory Surg., Fukushima Med. Univ.、6.Div.of Molec. Dx. & Cancer Prevent., Saitama Cancer Ctr.、7.Div. of Lower Gastrointest. Surg.,Dept. of Surg., Hyogo Col. of Med.、8.Dept. of Surg., Iwakuni Clin. Ctr.、9.Dept. of Surg., Tokyo Metro. Komagome Hosp.、10. Dept. of Digestive Tract & Gen. Surg., Saitama Med. Ctr., Saitama Med. Univ.)

Lynch syndrome、Mismatch repair genes、Next-generation sequencing、Genetic testing