The Japanese Biochemical Society/The Molecular Biology Society of Japan

[1P-1069] DNA-containing exosomes derived from cancer cells treated with Topotecan activate a STING-dependent pathway and reinforce antitumor immunity

〇Yuichi Kitai1,2, Jian Zou4, Takuya Sueyoshi2, Takumi Kawasaki2, Kouji Kobiyama3, Ken J. Ishii3, Shizuo Akira4, Tadashi Matsuda1, Taro Kawai2 (1.Dept. of Immunol., Grad. Sch. of Pharm., Univ. of Hokkaido, 2.Dept. of Immunol., Grad. Sch. of Biosci., NAIST, 3.Dept. of Vaccine, IFReC, Osaka Univ., 4.Dept. of Host Def., Res. Inst. Microbial Dis., Osaka Univ.)

DAMPs,、Immunogenic cell death、Antitumor drugs

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