The Japanese Biochemical Society/The Molecular Biology Society of Japan

[1P-1242] Analysis of Skeletal muscle pathology in spinal bulbar muscular atrophy (SBMA) by genome editing of CAG repeats

〇Satoshi Tanaka1,2, Takuji Ito1, Akinobu Ota3, Takefumi Sone4, Shiro Imagama2, Yoshitaka Hosokawa3, Hideyuki Okano4, Manabu Doyu1, Yohei Okada1 (1.Dept. of Neurol, Sch. of Med. Aichi Medical Univ., 2.Dept. of Orthop Surg, Sch. of Med. Nagoya Univ., 3.Dept. of Biochem, Sch. of Med. Aichi Medical Univ., 4.Dept. of Physiol, Sch. of Med. Keio Univ.)

Spinal Bulbar Muscular Atrophy、Polyglutamine disease、CRISPR/Cas9、Androgen receptor

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