The Japanese Biochemical Society/The Molecular Biology Society of Japan

[1P-1319] Generation of gene-modified rats by the GONAD, a novel in vivo genome editing system that does not require ex vivo handling of embryos

Tomoe Kobayashi1, Masumi Namba1, Takayuki Koyano1, Masahiro Sato2, Masato Ohtsuka3,4, 〇Makoto Matsuyama1 (1.Div. Mol. Genet., Shigei Med. Res. Inst., 2.Sec. of Gene Exp. Reg., Center for Adv. Biomed. Sci. and Swine Res., Kagoshima Univ., 3.Sch. of Med., Tokai Univ., 4.Inst. of Med. Sci., Tokai Univ.)

GONAD、Crispr-Cas9、Rat、Genome editing、electroporation

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