4:55 PM - 5:18 PM

[1PW21-3] In vitro model of CADASIL: iPS cell-derived mural cells for unraveling the pathogenesis of a hereditary small vessel disease

LOD 【E】

〇Yumi Yamamoto¹, Katsutoshi Kojima², Daisuke Taura², Masakatsu Sone², Kazuo Washida³, Naohiro Egawa⁴, Takayuki Kondo⁴, Eiko Minagawa⁵, Kayoko Tsukita⁴, Takako Eanmi⁴, Hidekazu Tomimoto⁶, Toshiki Mizuno⁷, Ryosuke Takahashi⁸, Masafumi Ihara⁹, Haruhisa Inoue⁴ (1.Dept. of Regen. Med. Tissue Eng., Nat. Cereb. Cardiovasc. Center Res. Institute, 2.Dept. of Diabetes, Endocrin. Nutr., Grad. Sch. of Med., Kyoto Univ., 3.Div. of Neurol., Grad. Sch. of Kobe Univ., 4.CiRA, Kyoto Univ., 5.Dept. of Degen. Neurol. Dis., National Institute of Neuroscience, Nat. Center of Neurol. and Psychiatr., 6.Dept. of Dementia Prevention and Therapeutics, Grad. Sch. of Med., Mie Univ., 7.Dept. of Neurol., Kyoto Prefectural Univ. of Med., 8.Dept. of Neurol., Kyoto Univ. Grad. Sch. of Med., 9.Dept. of Stroke and Cerebrovasc. Dis., Nat. Cereb. Cardiovasc. Center Res. Institute)

CADASIL、Hereditary small vessel disease、Notch3、Pericyte、Vascular dementia