The Japanese Biochemical Society/The Molecular Biology Society of Japan

4:55 PM - 5:18 PM

[1PW21-3] In vitro model of CADASIL: iPS cell-derived mural cells for unraveling the pathogenesis of a hereditary small vessel disease

LOD 【E】

〇Yumi Yamamoto1, Katsutoshi Kojima2, Daisuke Taura2, Masakatsu Sone2, Kazuo Washida3, Naohiro Egawa4, Takayuki Kondo4, Eiko Minagawa5, Kayoko Tsukita4, Takako Eanmi4, Hidekazu Tomimoto6, Toshiki Mizuno7, Ryosuke Takahashi8, Masafumi Ihara9, Haruhisa Inoue4 (1.Dept. of Regen. Med. Tissue Eng., Nat. Cereb. Cardiovasc. Center Res. Institute, 2.Dept. of Diabetes, Endocrin. Nutr., Grad. Sch. of Med., Kyoto Univ., 3.Div. of Neurol., Grad. Sch. of Kobe Univ., 4.CiRA, Kyoto Univ., 5.Dept. of Degen. Neurol. Dis., National Institute of Neuroscience, Nat. Center of Neurol. and Psychiatr., 6.Dept. of Dementia Prevention and Therapeutics, Grad. Sch. of Med., Mie Univ., 7.Dept. of Neurol., Kyoto Prefectural Univ. of Med., 8.Dept. of Neurol., Kyoto Univ. Grad. Sch. of Med., 9.Dept. of Stroke and Cerebrovasc. Dis., Nat. Cereb. Cardiovasc. Center Res. Institute)

CADASIL、Hereditary small vessel disease、Notch3、Pericyte、Vascular dementia

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