The Japanese Biochemical Society/The Molecular Biology Society of Japan

[2P-0443] M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells

〇Yasushi Hara1, Yuuki Obata1, Keita Horikawa1, Yasutaka Tasaki2, Kyohei Suzuki2, Takatsugu Murata2, Isamu Shiina2, Ryo Abe1 (1.Div. of Immunobiol., RIBS, Tokyo Univ. of Sci, 2.Dept. of Appl. chem., Fac. of Sci., Tokyo Univ. of Sci)

M-COPA、Kitチロシンキナーゼ、分子標的治療、PI3K-Akt、がんシグナリング

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