The Japanese Biochemical Society/The Molecular Biology Society of Japan

[2P-0808] MGP is a novel niche molecule that modulates normal and malignant hematopoietic stem/precursor cells

〇Aya Yokoi1, Chie Goto1, Kana Kuronuma1, Akio Maekawa1, Leo Matsubara1, Takako Fukunaga1, Natsumi Hasegawa1, Masamitsu Harata2, Shigetaka Asano2, Mitsuhiro Ito1,2,3 (1.Div. of Med. Biophysics, Grad. Sch. of Health Sci., Kobe Univ., 2.Res. Org. for Nano & Life Innov., Waseda Univ., 3.Lab. of Biochem. Mol. Biol., Rockefeller Univ.)

hematopoietic microenvironment、Mediator transcriptional coregulator complex, MED1、Matrix Gla protein (MGP)、leukemic stem cells

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