The Japanese Biochemical Society/The Molecular Biology Society of Japan

[2P-0883] Identification of the synthetic lethal gene to PARG dysfunction using inducible knockdown system

〇Yuka Sasaki1,2,3, Hiroaki Fujimori1,3, Miyuki Hozumi3,4, Yasufumi Murakami4, Fumiaki Koizumi5, Kengo Inoue6, Mitsuko Masutani1,2,3 (1.Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Div. Genetics, Natl. Cancer Ctr. Res. Inst., 3.Div. Chemother. and Clin. Res., Natl. Cancer Ctr. Res. Inst., 4.Tokyo Univ. Sci., Fac. Indus. Sci. Tech., 5.Div. Clin. Res. Support, Komagome Hosp., 6.Pharma Valley Center)

PARG、poly(ADP-ribose)、biomarker、PARP

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