The Japanese Biochemical Society/The Molecular Biology Society of Japan

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[2PW24-2] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Elicits Psychiatric Symptoms in FTLD

LOD 【J】

〇Ryo Endo1, Noriko Takashima1, Yoko Nekooki-Machida1, Yusuke Komi1, Kelvin Kai-Wan Hui1, Masaki Takao2,3, Hiroyasu Akatsu5,6, Shigeo Murayama2, Akira Sawa4, Motomasa Tanaka1 (1.RIKEN, Brain Sci. Inst., 2.Tokyo Metropolitan Geriatric Hospital and Inst. of Gerontology, 3.Dept. of Neurology., Saitama Med. Univ., 4.Dept. of Psychiatry, Johns Hopkins Univ., 5.Choju Med. Inst., Fukushimura Hospital, 6.Medical Nagoya City Univ. Grad. Sch. of Med. Sci.)

Co-aggregation、DISC1、Local translation

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