The Japanese Biochemical Society/The Molecular Biology Society of Japan

11:10 AM - 11:20 AM

[3AT12-14(3P-0236)] Investigation of mechanism of warfarin resistance of wild rats in Tokyo ~ enhanced pentose phosphate pathway causes rapid metabolism of warfarin ~

〇Kazuki Takeda1, Yoshinori Ikenaka1,2, Kazuyuki D. Tanaka3, Shouta M.M. Nakayama1, Tsutomu Tanikawa3, Hazuki Mizukawa1, Mayumi Ishizuka1 (1.Lab. of Tox., Grad. Sch. of Vet. Sci., Univ. of Hokkaido, 2.Gr. of Water Res., Unit for Environ. Sci. and Manage., Univ. of North West , 3.Tech. Res. Lab., IKARI SHODOKU CO., LTD., Japan)

cytochrome P450、pentose phosphate pathway、drug resistance、warfarin、metabolism

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