9:40 AM - 9:50 AM

[3AT25-05（3P-1440）] A novel FRET biosensor for necroptosis uncovers sequential regulation of the nuclear and cytoplasmic membrane rupture during DAMPs release

〇Shin Murai¹, Yoshifumi Yamaguchi^2,5, Yoshitaka Shirasaki³, Osamu Nakabayashi¹, Ryousuke Miura^1,4, Taichiro Tomida⁵, Satomi Adachi-Akahane⁵, Masayuki Miura², Hiroyasu Nakano^1,6 (1.Department of Biochemistry, Toho University School of Medicine, 2.Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 3.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 4.Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, 5.Department of Physiology, Toho University School of Medicine, 6.Host Defense Research Center, Toho University School of Medicine)

計画的ネクローシス、FRET、MLKL、RIPK3