The Japanese Biochemical Society/The Molecular Biology Society of Japan

[3LBA-001] X-ray crystal structures of Trastuzumab Fab bearing non-natural amino acids with azide functional group

〇Mitsuo Kuratani1, Tatsuo Yanagisawa1, Akifumi Kato2, Kazumasa Ohtake3, Akiko Hayashi3, Yoshimi Amano3, Kaname Kimura2, Yasuhisa Shiraishi4, Kensaku Sakamoto3, Shigeyuki Yokoyama1 (1.RIKEN Struct. Biol. Lab., 2.Kyowa Hakko Kirin Co., Ltd. Res. Core Funct. Lab., 3.RIKEN CLST, 4.Kyowa Hakko Kirin Co., Ltd. R&D Planning Group)

非天然型アミノ酸導入タンパク質、FAB抗体、トラスツズマブ、アジド基、Click反応

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