The Japanese Biochemical Society/The Molecular Biology Society of Japan

[3P-0159(4LT01-03)] Crystal structure of trimeric LUBAC reveals essential role of a novel HOIL-1L-SHARPIN interaction in LUBAC formation and function

〇Hiroaki Fujita1, Akira Tokunaga2, Masahiro Shirakawa2, Kazuhiro Iwai1 (1.Dept. of Mol. and Phys., Grad. Sch. of Med., Univ. of Kyoto, 2.Dept. of Mol. Eng., Grad. Sch. of Eng., Univ. of Kyoto)

LUBAC、直鎖状ポリユビキチン鎖

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