The Japanese Biochemical Society/The Molecular Biology Society of Japan

[3P-0209] Generation of genetically modified rats with CYP27B1 deficient or VDR mutation by genome editing to reveal molecular mechanism of vitamin D action

〇Miyu Nishikawa1, Kaori Yasuda1, Masashi Takamatsu1, Keisuke Abe1, Kyohei Horibe1, Kairi Okamoto1, Hiroki Mano1, Kimie Nakagawa2, Naoko Tsugawa3, Toshio Okano2, Shinichi Ikushiro1, Toshiyuki Sakaki1 (1.Fac. of Engineer., Toyama Pref. Univ., 2.Dep. of Hygenic Sci., Kobe Pharm. Univ., 3.Fac. of Health Nutr., Osaka Shoin Women's Univ.)

vitamim D、CYP27B1、VDR

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