The Japanese Biochemical Society/The Molecular Biology Society of Japan

[3P-0552(3PT18-06)] p53 binds to the CDH1 locus in epithelial cells to antagonize EZH2-mediated H3K27me3 deposition and the onset of mesenchymal programs

〇Tsukasa Oikawa1, Yutaro Otsuka1, Yasuhito Onodera1, Mei Horikawa1, Ari Hashimoto1, Shigeru Hashimoto1, Yutaka Suzuki2, Hisataka Sabe1 (1.Dept. of Mol. Biol, Hokkaido Univ. Grad. Sch. of Med., 2.Grad. Sch. of Frontier Sci., Univ. of Tokyo)

EMT、EZH2、H3K27me3、p53

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