The Japanese Biochemical Society/The Molecular Biology Society of Japan

ConBio2017

ConBio2017

Dec 6, 2017 - Dec 9, 2017
Kobe Port Island(Kobe International Conference Center, Kobe Portopia Hotel, Kobe International Exhibition Hall, The Kobe Chamber of Commerce and Industry)

[3P-1066（3PT26-12）] Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity

〇Natsumi Sakata1, Takahiro Horiuchi1, Yoshihiro Narumi1, Tomohiro Kimura1, Takashi Hayashi2, Keisuke Nagano2, Keyue Liu3, Masahiro Nishibori3, Sohei Tsukita4, Yamada Tetsuya4, Hideki Katagiri4, Ryutaro Shirakawa1, Hisanori Horiuchi1 (1.Dept. of Molecular and Cellular Biology, IDAC, Tohoku Univ., 2.Otsuka Pharmaceutical Co., Ltd., 3.Dept. of Pharmacology, Grad. Sch. of Med, Dent, and Pharmaceutical Sci., Okayama Univ., 4.Dept. of Metabolism and Diabetes, Grad. Sch. of Med, Tohoku. Univ.)

metformin、HMGB1、inflammation

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