The Japanese Biochemical Society/The Molecular Biology Society of Japan

ConBio2017

ConBio2017

Dec 6, 2017 - Dec 9, 2017
Kobe Port Island(Kobe International Conference Center, Kobe Portopia Hotel, Kobe International Exhibition Hall, The Kobe Chamber of Commerce and Industry)

[3P-1083（4P1T06-15）] Discovery of novel anti-diabetic drugs by interrupting the DGKζ and IRS-1 interaction

〇Bu Chin Yu1, Akihiro Ito2, Minoru Yoshida2, Yasutoshi Ando1, Fumihiko Hukuno1, Shin-Ichiro Takahashi1 (1.Dept. of Animal Sciences and Applied Biological Chemistry, Grad.Sch. of Agriculture and Life Sciences., Univ. of Tokyo, 2.Chemical Genetics Laboratory, RIKEN)

Type 2 diabetes mellitus、Insulin receptor substrate (IRS)、Tumor necrosis factor α(TNFα)、Glucose transporter 4 (GLUT4)、Diacylgltcerol kinase ζ (DGKζ)

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